Down-regulation of cyclin-dependent kinase 5 attenuates p53-dependent apoptosis of hippocampal CA1 pyramidal neurons following transient cerebral ischemia

Abnormal activation of cyclin-dependent kinase 5 (Cdk5) is associated with pathophysiological conditions. Ischemic preconditioning (IPC) can provide neuroprotective effects against subsequent lethal ischemic insult. The objective of this study was to determine how Cdk5 and related molecules could af...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Shin, Bich Na, Kim, Dae Won, Kim, In Hye, Park, Joon Ha, Ahn, Ji Hyeon, Kang, Il Jun, Lee, Yun Lyul, Lee, Choong-Hyun, Hwang, In Koo, Kim, Young-Myeong, Ryoo, Sungwoo, Lee, Tae-Kyeong, Won, Moo-Ho, Lee, Jae-Chul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737192/
https://ncbi.nlm.nih.gov/pubmed/31506563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49623-x
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg