miRNA-dependent regulation of STIM1 expression in breast cancer

Store-operated Ca(2+) entry (SOCE) has been shown to be important for breast cancer metastasis in xenograft mouse models. The ER Ca(2+) sensor STIM1 and Orai plasma membrane Ca(2+) channels molecularly mediate SOCE. Here we investigate the role of the microRNA machinery in regulating STIM1 expressio...

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Udgivet i:Sci Rep
Main Authors: Kulkarni, Rashmi P., Elmi, Asha, Alcantara-Adap, Ethel, Hubrack, Satanay, Nader, Nancy, Yu, Fang, Dib, Maya, Ramachandran, Vimal, Najafi Shoushtari, Hani, Machaca, Khaled
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736934/
https://ncbi.nlm.nih.gov/pubmed/31506588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49629-5
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