The availability of drug by liposomal drug delivery: Individual kinetics and tissue distribution of encapsulated and released drug in mice after administration of PEGylated liposomal prednisolone phosphate

Lately, the usefulness of liposomal drug delivery systems has been debated. To better understand the underlying pharmacokinetics of the targeted drug delivery by liposomes, individual encapsulated and non-encapsulated drug concentrations in blood, tumor, liver, spleen and kidneys were quantified aft...

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Bibliografiska uppgifter
I publikationen:Invest New Drugs
Huvudupphovsmän: Smits, Evelien A. W., Soetekouw, José A., Pieters, Ebel H. E., Smits, Coen J. P., de Wijs-Rot, Nicolette, Vromans, Herman
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2018
Ämnen:
Preclinical Studies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736927/
https://ncbi.nlm.nih.gov/pubmed/30547315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-018-0708-4
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