The availability of drug by liposomal drug delivery: Individual kinetics and tissue distribution of encapsulated and released drug in mice after administration of PEGylated liposomal prednisolone phosphate

Lately, the usefulness of liposomal drug delivery systems has been debated. To better understand the underlying pharmacokinetics of the targeted drug delivery by liposomes, individual encapsulated and non-encapsulated drug concentrations in blood, tumor, liver, spleen and kidneys were quantified aft...

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Dades bibliogràfiques
Publicat a:Invest New Drugs
Autors principals: Smits, Evelien A. W., Soetekouw, José A., Pieters, Ebel H. E., Smits, Coen J. P., de Wijs-Rot, Nicolette, Vromans, Herman
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
Matèries:
Preclinical Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736927/
https://ncbi.nlm.nih.gov/pubmed/30547315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-018-0708-4
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