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PEGylated Liposome Encapsulation Increases the Lung Tissue Concentration of Vancomycin

Pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA) often cannot be cured by vancomycin treatment. Poor lung tissue and intracellular penetration limits the ability to achieve effective bactericidal levels, particularly in alveolar macrophages, where MRSA can evade phagocytic killing...

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Detalhes bibliográficos
Main Authors: Muppidi, Krishna, Wang, Jeffrey, Betageri, Guru, Pumerantz, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186981/
https://ncbi.nlm.nih.gov/pubmed/21788465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00713-11
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