Metallopanstimulin-1 (MPS-1) mediates the promotion effect of leptin on colorectal cancer through activation of JNK/c-Jun signaling pathway

Obesity is a major epigenetic cause for colorectal cancer (CRC). Leptin is implicated in obesity-associated CRC, but the underlying mechanism remains unclear. The current study identified over-expression of metallopanstimulin-1 (MPS-1) in CRC patients through microarray and histological analysis, es...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Cao, Dongxing, Luo, Yang, Qin, Shaolan, Yu, Minhao, Mu, Yifei, Ye, Guangyao, Yang, Nailin, Cong, Zhijie, Chen, Jianjun, Qin, Jun, Cui, Ran, Jing, Ran, Cao, Hui, Zhong, Ming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736844/
https://ncbi.nlm.nih.gov/pubmed/31506433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1911-8
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