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Two novel mutations of PEX6 in one Chinese Zellweger spectrum disorder and their clinical characteristics

BACKGROUND: Zellweger spectrum disorder (ZSD) is an autosomal recessive peroxisome biogenesis disorder (PBD) caused by bi-allelic mutations in any of the 13 PEX family genes. METHODS: We reported a Chinese PBD-ZSD patient with compound heterozygous mutations of PEX6 detected by target sequencing and...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Yu, Hui-Ling, Shen, Yan, Sun, Yi-Min, Zhang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736815/
https://ncbi.nlm.nih.gov/pubmed/31555682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.06.42
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