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Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer

Constitutive activation of the Hedgehog (Hh) signaling pathway is associated with increased risk of developing several malignancies. The biological and pathogenic importance of Hh signaling emphasizes the need to control its action tightly, both physiologically and therapeutically. Evidence of cross...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Pelullo, Maria, Zema, Sabrina, Nardozza, Francesca, Checquolo, Saula, Screpanti, Isabella, Bellavia, Diana
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736567/
https://ncbi.nlm.nih.gov/pubmed/31552081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00711
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