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Misrepair in Context: TGFβ Regulation of DNA Repair

Repair of DNA damage protects genomic integrity, which is key to tissue functional integrity. In cancer, the type and fidelity of DNA damage response is the fundamental basis for clinical response to cytotoxic therapy. Here we consider the contribution of transforming growth factor-beta (TGFβ), a ub...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Liu, Qi, Lopez, Kirsten, Murnane, John, Humphrey, Timothy, Barcellos-Hoff, Mary Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736563/
https://ncbi.nlm.nih.gov/pubmed/31552165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00799
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