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COMP-10. ANTI-CORRELATED TGFβ AND ALTERNATIVE END-JOINING DNA REPAIR SIGNATURES ASSOCIATE WITH OUTCOME IN PRIMARY GBM
Transforming growth factor β (TGFβ), which is distinctively overexpressed in glioblastoma (GBM) while undetectable in normal brain tissue, could underlie GBM intrinsic radioresistance by endorsing effective DNA damage responses. We showed that most (5/7) primary GBM explants respond to TGFβ and are...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217096/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.265 |
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