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Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population

Organophosphates have a long history of use as insecticides over the world. The aim of the present study was to investigate the interethnic differences in kinetics, biomarker formation, and in vivo red blood cell acetylcholinesterase inhibition of chlorpyrifos (CPF) in the Chinese and the Caucasian...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Zhao, Shensheng, Kamelia, Lenny, Boonpawa, Rungnapa, Wesseling, Sebastiaan, Spenkelink, Bert, Rietjens, Ivonne M C M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736452/
https://ncbi.nlm.nih.gov/pubmed/31214721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz134
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