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Yeast cells can partially revert chromosome segregation to repair late DNA double-strand breaks through homologous recombination

DNA repair in late mitosis sets paradoxical scenarios. Cyclin-dependent kinase (CDK) activity is high, which favors homologous recombination (HR), despite a sister chromatid is not physically close to recombine with. We have found that DNA double-strand breaks partially revert chromosome segregation...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Ayra-Plasencia, Jessel, Machín, Félix
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736361/
https://ncbi.nlm.nih.gov/pubmed/31528706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1648027
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