DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling

A DNA molecule is under continuous influence of endogenous and exogenous damaging factors, which produce a variety of DNA lesions. Apurinic/apyrimidinic sites (abasic or AP sites) are among the most common DNA lesions. In this work, we applied pulse dipolar electron paramagnetic resonance (EPR) spec...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Krumkacheva, Olesya A, Shevelev, Georgiy Yu, Lomzov, Alexander A, Dyrkheeva, Nadezhda S, Kuzhelev, Andrey A, Koval, Vladimir V, Tormyshev, Victor M, Polienko, Yuliya F, Fedin, Matvey V, Pyshnyi, Dmitrii V, Lavrik, Olga I, Bagryanskaya, Elena G
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Chemical Biology and Nucleic Acid Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735896/
https://ncbi.nlm.nih.gov/pubmed/31329919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz620
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