DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling

A DNA molecule is under continuous influence of endogenous and exogenous damaging factors, which produce a variety of DNA lesions. Apurinic/apyrimidinic sites (abasic or AP sites) are among the most common DNA lesions. In this work, we applied pulse dipolar electron paramagnetic resonance (EPR) spec...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Krumkacheva, Olesya A, Shevelev, Georgiy Yu, Lomzov, Alexander A, Dyrkheeva, Nadezhda S, Kuzhelev, Andrey A, Koval, Vladimir V, Tormyshev, Victor M, Polienko, Yuliya F, Fedin, Matvey V, Pyshnyi, Dmitrii V, Lavrik, Olga I, Bagryanskaya, Elena G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Chemical Biology and Nucleic Acid Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735896/
https://ncbi.nlm.nih.gov/pubmed/31329919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz620
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