The Central Role of Protein Kinase C Epsilon in Cyanide Cardiotoxicity and Its Treatment

In adult mouse myocytes, brief exposure to sodium cyanide (CN) in the presence of glucose does not decrease ATP levels, yet produces profound reduction in contractility, intracellular Ca(2+) concentration ([Ca(2+)](i)) transient and L-type Ca(2+) current (I(Ca)) amplitudes. We analyzed proteomes fro...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Cheung, Joseph Y, Merali, Salim, Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Merali, Carmen, Tomar, Dhanendra, You, Hanning, Judenherc-Haouzi, Annick, Haouzi, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Organ Specific Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735853/
https://ncbi.nlm.nih.gov/pubmed/31173149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz137
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