The dynamics of forming a triplex in an artificial telomere inferred by DNA mechanics

A telomere carrying repetitive sequences ends with a single-stranded overhang. The G-rich overhang could fold back and bind in the major groove of its upstream duplex, forming an antiparallel triplex structure. The telomeric triplex has been proposed to function in protecting chromosome ends. Howeve...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Ning, Wang, Junli, Ma, Kangkang, Liang, Lin, Mi, Lipei, Huang, Wei, Ma, Xiaofeng, Wang, Zeyu, Zheng, Wei, Xu, Linyan, Chen, Jun-Hu, Yu, Zhongbo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735771/
https://ncbi.nlm.nih.gov/pubmed/31114915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz464
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