Differences in mutational processes and intra-tumour heterogeneity between organs: The local selective filter hypothesis

Extensive diversity (genetic, cytogenetic, epigenetic and phenotypic) exists within and between tumours, but reasons behind these variations, as well as their consistent hierarchical pattern between organs, are poorly understood at the moment. We argue that these phenomena are, at least partially, e...

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Bibliografiske detaljer
Udgivet i:Evol Med Public Health
Main Authors: Giraudeau, Mathieu, Sepp, Tuul, Ujvari, Beata, Renaud, François, Tasiemski, Aurélie, Roche, Benjamin, Capp, Jean-Pascal, Thomas, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Commentary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735757/
https://ncbi.nlm.nih.gov/pubmed/31528343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eoz017
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