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Early postnatal overnutrition accelerates aging-associated epigenetic drift in pancreatic islets
Pancreatic islets of type 2 diabetes patients have altered DNA methylation, contributing to islet dysfunction and the onset of type 2 diabetes. The cause of these epigenetic alterations is largely unknown. We set out to test whether (i) islet DNA methylation would change with aging and (ii) early po...
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| Publicat a: | Environ Epigenet |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735752/ https://ncbi.nlm.nih.gov/pubmed/31528363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvz015 |
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