Increasing the low lipid phosphate phosphatase 1 activity in breast cancer cells decreases transcription by AP-1 and expressions of matrix metalloproteinases and cyclin D1/D3

Metastasis is the leading cause of mortality in breast cancer patients and lysophosphatidate (LPA) signaling promotes this process. LPA signaling is attenuated by lipid phosphate phosphatase-1 (LPP1) whose activity is decreased in cancers. Consequently, increasing LPP1 levels suppresses breast tumor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Theranostics
Egile Nagusiak: Tang, Xiaoyun, McMullen, Todd P.W., Brindley, David N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735510/
https://ncbi.nlm.nih.gov/pubmed/31534541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37094
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