Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice

Lipid phosphate phosphatase-1 (LPP1) degrades lysophosphatidate (LPA) and attenuates receptor-mediated signaling. LPP1 expression is low in many cancer cells and tumors compared with normal tissues. It was hypothesized from studies with cultured cells that increasing LPP1 activity would decrease tum...

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Detaylı Bibliyografya
Yayımlandı:J Lipid Res
Asıl Yazarlar: Tang, Xiaoyun, Benesch, Matthew G. K., Dewald, Jay, Zhao, Yuan Y., Patwardhan, Neeraj, Santos, Webster L., Curtis, Jonathan M., McMullen, Todd P. W., Brindley, David N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2014
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617140/
https://ncbi.nlm.nih.gov/pubmed/25210149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M053462
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