CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer

Rationale: Colorectal cancer (CRC) is one of the most common cancers worldwide. Ciclopirox olamine (CPX) has recently been identified to be a promising anticancer candidate; however, novel activities and detailed mechanisms remain to be uncovered. Methods: The cytotoxic potential of CPX towards CRC...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhou, Jing, Zhang, Lu, Wang, Meng, Zhou, Li, Feng, Xuping, Yu, Linli, Lan, Jiang, Gao, Wei, Zhang, Chundong, Bu, Youquan, Huang, Canhua, Zhang, Haiyuan, Lei, Yunlong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735393/
https://ncbi.nlm.nih.gov/pubmed/31534504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.34663
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