Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells

Betulinic acid (BA) exhibits cytotoxic activity against some cancer cells. However, the molecular mechanism of BA against CRC cells was little reported. Here, we proved that BA elicited CRC cells' growth inhibition and apoptosis in a dose-dependent manner. In addition, BA treatment induced auto...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Dis
Main Authors: Wang, Sen, Wang, Kexin, Zhang, Chundong, Zhang, Wanfeng, Xu, Qian, Wang, Yitao, Zhang, Yulin, Li, Yi, Zhang, Ying, Zhu, Huifang, Song, Fangzhou, Lei, Yunlong, Bu, Youquan
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2017
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682653/
https://ncbi.nlm.nih.gov/pubmed/28981110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.485
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