Biodegradable, pH-Sensitive Hollow Mesoporous Organosilica Nanoparticle (HMON) with Controlled Release of Pirfenidone and Ultrasound-Target-Microbubble-Destruction (UTMD) for Pancreatic Cancer Treatment

The dense extracellular matrix (ECM) and hypovascular networks were often found in solid pancreatic tumors form an impenetrable barrier, leading to limited uptake of chemotherapeutics and thus undesirable treatment outcomes. Methods: A biodegradable nanoplatform based on hollow mesoporous organosili...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Gao, Feng, Wu, Jianrong, Niu, Shiwei, Sun, Ting, Li, Fan, Bai, Yun, Jin, Lifang, Lin, Lizhou, Shi, Qiusheng, Zhu, Li-Min, Du, Lianfang
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735371/
https://ncbi.nlm.nih.gov/pubmed/31534533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36135
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