Biodegradable, pH-Sensitive Hollow Mesoporous Organosilica Nanoparticle (HMON) with Controlled Release of Pirfenidone and Ultrasound-Target-Microbubble-Destruction (UTMD) for Pancreatic Cancer Treatment

The dense extracellular matrix (ECM) and hypovascular networks were often found in solid pancreatic tumors form an impenetrable barrier, leading to limited uptake of chemotherapeutics and thus undesirable treatment outcomes. Methods: A biodegradable nanoplatform based on hollow mesoporous organosili...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Gao, Feng, Wu, Jianrong, Niu, Shiwei, Sun, Ting, Li, Fan, Bai, Yun, Jin, Lifang, Lin, Lizhou, Shi, Qiusheng, Zhu, Li-Min, Du, Lianfang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735371/
https://ncbi.nlm.nih.gov/pubmed/31534533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36135
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