Extrinsic acidosis suppresses glycolysis and migration while increasing network formation in pulmonary microvascular endothelial cells

Acidosis is common among critically ill patients, but current approaches to correct pH do not improve disease outcomes. During systemic acidosis, cells are either passively exposed to extracellular acidosis that other cells have generated (extrinsic acidosis) or they are exposed to acid that they ge...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: Lee, Ji Young, Onanyan, Mher, Garrison, Ian, White, Roderica, Crook, Maura, Alexeyev, Mikhail F., Kozhukhar, Natalya, Pastukh, Viktoriya, Swenson, Erik R., Supuran, Claudiu T., Stevens, Troy
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734381/
https://ncbi.nlm.nih.gov/pubmed/31042076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00544.2018
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