Extrinsic acidosis suppresses glycolysis and migration while increasing network formation in pulmonary microvascular endothelial cells

Acidosis is common among critically ill patients, but current approaches to correct pH do not improve disease outcomes. During systemic acidosis, cells are either passively exposed to extracellular acidosis that other cells have generated (extrinsic acidosis) or they are exposed to acid that they ge...

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Опубликовано в: :Am J Physiol Lung Cell Mol Physiol
Главные авторы: Lee, Ji Young, Onanyan, Mher, Garrison, Ian, White, Roderica, Crook, Maura, Alexeyev, Mikhail F., Kozhukhar, Natalya, Pastukh, Viktoriya, Swenson, Erik R., Supuran, Claudiu T., Stevens, Troy
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734381/
https://ncbi.nlm.nih.gov/pubmed/31042076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00544.2018
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