Extrinsic acidosis suppresses glycolysis and migration while increasing network formation in pulmonary microvascular endothelial cells

Acidosis is common among critically ill patients, but current approaches to correct pH do not improve disease outcomes. During systemic acidosis, cells are either passively exposed to extracellular acidosis that other cells have generated (extrinsic acidosis) or they are exposed to acid that they ge...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Lee, Ji Young, Onanyan, Mher, Garrison, Ian, White, Roderica, Crook, Maura, Alexeyev, Mikhail F., Kozhukhar, Natalya, Pastukh, Viktoriya, Swenson, Erik R., Supuran, Claudiu T., Stevens, Troy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734381/
https://ncbi.nlm.nih.gov/pubmed/31042076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00544.2018
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