Extrinsic acidosis suppresses glycolysis and migration while increasing network formation in pulmonary microvascular endothelial cells

Acidosis is common among critically ill patients, but current approaches to correct pH do not improve disease outcomes. During systemic acidosis, cells are either passively exposed to extracellular acidosis that other cells have generated (extrinsic acidosis) or they are exposed to acid that they ge...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Lee, Ji Young, Onanyan, Mher, Garrison, Ian, White, Roderica, Crook, Maura, Alexeyev, Mikhail F., Kozhukhar, Natalya, Pastukh, Viktoriya, Swenson, Erik R., Supuran, Claudiu T., Stevens, Troy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734381/
https://ncbi.nlm.nih.gov/pubmed/31042076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00544.2018
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