Acetaldehyde suppresses the display of HBV-MHC class I complexes on HBV-expressing hepatocytes

Hepatitis B virus (HBV) infection and alcoholism are major public health problems worldwide, contributing to the development of end-stage liver disease. Alcohol intake affects HBV infection pathogenesis and treatment outcomes. HBV-specific cytotoxic T lymphocytes (CTLs) play an important role in HBV...

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Udgivet i:Am J Physiol Gastrointest Liver Physiol
Main Authors: Ganesan, Murali, Krutik, Vjaceslav M., Makarov, Edward, Mathews, Saumi, Kharbanda, Kusum K., Poluektova, Larisa Y., Casey, Carol A, Osna, Natalia A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734374/
https://ncbi.nlm.nih.gov/pubmed/31141391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00064.2019
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