Opsonic monoclonal antibodies enhance phagocytic killing activity and clearance of Mycobacterium tuberculosis from blood in a quantitative qPCR mouse model

BACKGROUND: Patients with impaired immunity often have rapid progression of tuberculosis (TB) which can lead to highly lethal Mycobacterium tuberculosis (MTB) sepsis. Opsonic monoclonal antibodies (MABs) directed against MTB that enhance phagocytic killing activity and clearance of MTB from blood ma...

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Vydáno v:Heliyon
Hlavní autoři: Sei, Clara J., Shey, Bong-Akee, Schuman, Richard F., Rikhi, Nimisha, Muema, Kevin, Rodriguez, John D., Daum, Luke T., Fourie, P. Bernard, Fischer, Gerald W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734336/
https://ncbi.nlm.nih.gov/pubmed/31517107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e02260
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