Opsonic monoclonal antibodies enhance phagocytic killing activity and clearance of Mycobacterium tuberculosis from blood in a quantitative qPCR mouse model

BACKGROUND: Patients with impaired immunity often have rapid progression of tuberculosis (TB) which can lead to highly lethal Mycobacterium tuberculosis (MTB) sepsis. Opsonic monoclonal antibodies (MABs) directed against MTB that enhance phagocytic killing activity and clearance of MTB from blood ma...

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Pubblicato in:Heliyon
Autori principali: Sei, Clara J., Shey, Bong-Akee, Schuman, Richard F., Rikhi, Nimisha, Muema, Kevin, Rodriguez, John D., Daum, Luke T., Fourie, P. Bernard, Fischer, Gerald W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734336/
https://ncbi.nlm.nih.gov/pubmed/31517107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e02260
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