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Regulation of erythropoiesis after normoxic return from chronic sustained and intermittent hypoxia

Hypoxia increases erythropoiesis mediated by hypoxia-inducible transcription factors (HIF), which regulate erythropoietin transcription. Neocytolysis is a physiological mechanism that corrects polycythemia from chronic sustained hypoxemia by transient, preferential destruction of young RBCs after no...

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Pubblicato in:J Appl Physiol (1985)
Autori principali: Song, Jihyun, Sundar, Krishna, Gangaraju, Radhika, Prchal, Josef T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734089/
https://ncbi.nlm.nih.gov/pubmed/28522758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00119.2017
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