Mitochondrial dysfunction in iPSC-derived neurons of subjects with chronic mountain sickness

Patients with chronic mountain sickness (CMS) suffer from hypoxemia, erythrocytosis, and numerous neurologic deficits. Here we used induced pluripotent stem cell (iPSC)-derived neurons from both CMS and non-CMS subjects to study CMS neuropathology. Using transmission electron microscopy, we report t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Appl Physiol (1985)
Hlavní autoři: Zhao, Helen, Perkins, Guy, Yao, Hang, Callacondo, David, Appenzeller, Otto, Ellisman, Mark, La Spada, Albert R., Haddad, Gabriel G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734077/
https://ncbi.nlm.nih.gov/pubmed/29357502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00689.2017
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky