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Localization and stretch-dependence of lung elastase activity in development and compensatory growth

Synthesis and remodeling of the lung matrix is necessary for primary and compensatory lung growth. Because cyclic negative force is applied to developing lung tissue during the respiratory cycle, we hypothesized that stretch is a critical regulator of lung matrix remodeling. By using quantitative im...

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Pubblicato in:J Appl Physiol (1985)
Autori principali: Young, Sarah Marie, Liu, Sheng, Joshi, Rashika, Batie, Matthew R., Kofron, Matthew, Guo, Jinbang, Woods, Jason C., Varisco, Brian Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734075/
https://ncbi.nlm.nih.gov/pubmed/25614601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00954.2014
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