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Synthesis and Evaluations of Novel Apocynin Derivatives as Anti-Glioma Agents
Apocynin (4-hydroxy-3-methoxyacetophenone) is a natural polyphenolic compound with multiple biological activities. In the present study, a series of apocynin derivatives were designed and synthesized. The in silico ADMET prediction, blood–brain barrier (BBB) penetration assay, anti-NADPH oxidase act...
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| Опубликовано в: : | Front Pharmacol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733959/ https://ncbi.nlm.nih.gov/pubmed/31551769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00951 |
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