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Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents

In the clinic some anti-tumor drugs have shown damage to normal blood vessels, which could lead to vascular diseases. Therefore, it is necessary to evaluate the effects of anti-tumor drugs on normal blood vessels at the beginning of the drug design process. In this study, ligustrazine (TMP) and flav...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wang, Hui, Zhang, Wenxi, Cheng, Yatao, Zhang, Xinyu, Xue, Nannan, Wu, Gaorong, Chen, Meng, Fang, Kang, Guo, Wenbo, Zhou, Fei, Cui, Herong, Ma, Tao, Wang, Penglong, Lei, Haimin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225232/
https://ncbi.nlm.nih.gov/pubmed/30200208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092187
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