Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents

The solubilization of membranes by detergents is critical for many technological applications and has become widely used in biochemistry research to induce cell rupture, extract cell constituents, and to purify, reconstitute and crystallize membrane proteins. The thermodynamic details of solubilizat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dalgarno, Paul A., Juan-Colás, José, Hedley, Gordon J., Piñeiro, Lucas, Novo, Mercedes, Perez-Gonzalez, Cibran, Samuel, Ifor D. W., Leake, Mark C., Johnson, Steven, Al-Soufi, Wajih, Penedo, J. Carlos, Quinn, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733941/
https://ncbi.nlm.nih.gov/pubmed/31501469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49210-0
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