Formyl Peptide Receptor 2 Activation Ameliorates Dermal Fibrosis and Inflammation in Bleomycin-Induced Scleroderma

Systemic sclerosis is a profibrotic autoimmune disease mediated by the dysregulation of extracellular matrix synthesis. Formyl peptide receptor 2 (Fpr2) is a G protein-coupled receptor that modulates inflammation and host defense by regulating the activation of inflammatory cells, such as macrophage...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Park, Gyu Tae, Kwon, Yang Woo, Lee, Tae Wook, Kwon, Seong Gyu, Ko, Hyun-Chang, Kim, Moon Bum, Kim, Jae Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733889/
https://ncbi.nlm.nih.gov/pubmed/31552041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02095
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