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IFN-γ restores the impaired function of RNase L and induces mitochondria-mediated apoptosis in lung cancer

RNase L is an essential component in interferon (IFN)-mediated antiviral signaling that showed antitumor effects in cancer. Cancer immunotherapy based on interferon has achieved encouraging results that indicate an applicable potential for cancer therapy. Here we showed that function of RNase L, tho...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Yin, Huijing, Jiang, Zhengyu, Wang, Shuoer, Zhang, Ping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733796/
https://ncbi.nlm.nih.gov/pubmed/31501431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1902-9
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