Polycystin-1 assembles with Kv channels to govern cardiomyocyte repolarization and contractility

BACKGROUND: Polycystin-1 (PC1) is a transmembrane protein originally identified in autosomal dominant polycystic kidney disease (ADPKD) where it regulates the calcium-permeant cation channel polycystin-2. ADPKD patients develop renal failure, hypertension, left ventricular hypertrophy, atrial fibril...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Altamirano, Francisco, Schiattarella, Gabriele G., French, Kristin M., Kim, Soo Young, Engelberger, Felipe, Kyrychenko, Sergii, Villalobos, Elisa, Tong, Dan, Schneider, Jay W., Ramirez-Sarmiento, Cesar A., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733647/
https://ncbi.nlm.nih.gov/pubmed/31220931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.034731
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