Evidence that a positive feedback loop drives centrosome maturation in fly embryos

Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn are thought to for...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Alvarez-Rodrigo, Ines, Steinacker, Thomas L, Saurya, Saroj, Conduit, Paul T, Baumbach, Janina, Novak, Zsofia A, Aydogan, Mustafa G, Wainman, Alan, Raff, Jordan W
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733597/
https://ncbi.nlm.nih.gov/pubmed/31498081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50130
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