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Evidence that a positive feedback loop drives centrosome maturation in fly embryos

Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn are thought to for...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Alvarez-Rodrigo, Ines, Steinacker, Thomas L, Saurya, Saroj, Conduit, Paul T, Baumbach, Janina, Novak, Zsofia A, Aydogan, Mustafa G, Wainman, Alan, Raff, Jordan W
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733597/
https://ncbi.nlm.nih.gov/pubmed/31498081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50130
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