Evidence that a positive feedback loop drives centrosome maturation in fly embryos

Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn are thought to for...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Alvarez-Rodrigo, Ines, Steinacker, Thomas L, Saurya, Saroj, Conduit, Paul T, Baumbach, Janina, Novak, Zsofia A, Aydogan, Mustafa G, Wainman, Alan, Raff, Jordan W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733597/
https://ncbi.nlm.nih.gov/pubmed/31498081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50130
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