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Adverse Effect of Catechol-O-Methyltransferase (COMT) Val158Met Met/Met Genotype in Methamphetamine-related Executive Dysfunction
INTRODUCTION: The Val allele of the Val158Met single-nucleotide polymorphism of the catechol-o-methyltransferase gene (COMT) confers greater catabolism of dopamine (DA) in the prefrontal cortex (PFC) than the Met allele. Met/Met homozygotes typically outperform Val-carriers on tests of executive fun...
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| Pubblicato in: | Addict Behav |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733518/ https://ncbi.nlm.nih.gov/pubmed/31301644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addbeh.2019.06.012 |
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