Minocycline Inhibits PDGF-BB-induced Human Aortic Smooth Muscle Cell Proliferation and Migration by reversing miR-221- and -222-mediated RECK suppression

Minocycline, a tetracycline antibiotic, is known to exert vasculoprotective effects independent of its anti-bacterial properties; however the underlying molecular mechanisms are not completely understood. Reversion Inducing Cysteine Rich Protein with Kazal Motifs (RECK) is a cell surface expressed,...

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Bibliographic Details
Published in:Cell Signal
Main Authors: Higashi, Yusuke, Srinivas, Mummidi, Sukhanov, Sergiy, Yoshida, Tadashi, Noda, Makoto, Delafontaine, Patrice, Chandrasekar, Bysani
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732797/
https://ncbi.nlm.nih.gov/pubmed/30716386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.01.014
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