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Sustained hypoxemia in late gestation potentiates hepatic gluconeogenic gene expression but does not activate glucose production in the ovine fetus

Fetal hypoxemia is associated with pregnancy conditions that cause an early activation of fetal glucose production. However, the independent role of hypoxemia to activate this pathway is not well understood. We hypothesized that fetal hypoxemia would activate fetal glucose production by decreasing u...

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Bibliographic Details
Published in:Am J Physiol Endocrinol Metab
Main Authors: Jones, Amanda K., Rozance, Paul J., Brown, Laura D., Goldstrohm, David A., Hay, William W., Limesand, Sean W., Wesolowski, Stephanie R.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732654/
https://ncbi.nlm.nih.gov/pubmed/30964701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00069.2019
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