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Sustained hypoxemia in late gestation potentiates hepatic gluconeogenic gene expression but does not activate glucose production in the ovine fetus

Fetal hypoxemia is associated with pregnancy conditions that cause an early activation of fetal glucose production. However, the independent role of hypoxemia to activate this pathway is not well understood. We hypothesized that fetal hypoxemia would activate fetal glucose production by decreasing u...

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Опубликовано в: :Am J Physiol Endocrinol Metab
Главные авторы: Jones, Amanda K., Rozance, Paul J., Brown, Laura D., Goldstrohm, David A., Hay, William W., Limesand, Sean W., Wesolowski, Stephanie R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732654/
https://ncbi.nlm.nih.gov/pubmed/30964701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00069.2019
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