Genetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case–control study

BACKGROUND: A total of 50 million persons were diagnosed worldwide with epilepsy. One-third of them are experiencing debilitating seizures despite optimum anti‐epileptic drugs (AEDs) treatment. Several studies have suggested that CYP3A5, CHRM2, and ZNF498 influence the pharmacokinetics of AEDs. Ther...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmgenomics Pers Med
मुख्य लेखकों: AL-Eitan, Laith N, Al-Dalalah, Islam M, Mustafa, Mohamed M, Alghamdi, Mansour A, Elshammari, Afrah K, Khreisat, Wael H, Al-Quasmi, Mohammed N, Aljamal, Hanan A
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove 2019
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732506/
https://ncbi.nlm.nih.gov/pubmed/31564953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S212433
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