Genetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case–control study

BACKGROUND: A total of 50 million persons were diagnosed worldwide with epilepsy. One-third of them are experiencing debilitating seizures despite optimum anti‐epileptic drugs (AEDs) treatment. Several studies have suggested that CYP3A5, CHRM2, and ZNF498 influence the pharmacokinetics of AEDs. Ther...

詳細記述

保存先:
書誌詳細
出版年:Pharmgenomics Pers Med
主要な著者: AL-Eitan, Laith N, Al-Dalalah, Islam M, Mustafa, Mohamed M, Alghamdi, Mansour A, Elshammari, Afrah K, Khreisat, Wael H, Al-Quasmi, Mohammed N, Aljamal, Hanan A
フォーマット: Artigo
言語:Inglês
出版事項: Dove 2019
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732506/
https://ncbi.nlm.nih.gov/pubmed/31564953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S212433
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