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Activation of cryptic splice sites in three patients with chronic granulomatous disease

BACKGROUND: Chronic granulomatous disease (CGD) is a primary immune deficiency caused by mutations in the genes encoding the structural components of the phagocyte NADPH oxidase. As a result, the patients cannot generate sufficient amounts of reactive oxygen species required for killing pathogenic m...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: de Boer, Martin, van Leeuwen, Karin, Hauri‐Hohl, Mathias, Roos, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732321/
https://ncbi.nlm.nih.gov/pubmed/31364312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.854
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