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Five novel NF1 gene pathogenic variants in 10 different Chinese families with neurofibromatosis type 1

BACKGROUND: Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with equal sex incidence that is characterized by neurofibromas, café‐au‐lait macules, axillary freckling, optic pathway tumor, distinctive osseous lesion, and iris Lisch nodules. Inactivating variants in the NF1 gene have...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Chen, Linlin, Xue, Feng, Xu, Jia, He, Jinwei, Fu, Wenzhen, Zhang, Zhenlin, Kang, Qinglin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732320/
https://ncbi.nlm.nih.gov/pubmed/31347283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.904
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