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Five novel NF1 gene pathogenic variants in 10 different Chinese families with neurofibromatosis type 1

BACKGROUND: Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with equal sex incidence that is characterized by neurofibromas, café‐au‐lait macules, axillary freckling, optic pathway tumor, distinctive osseous lesion, and iris Lisch nodules. Inactivating variants in the NF1 gene have...

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Bibliografiska uppgifter
I publikationen:Mol Genet Genomic Med
Huvudupphovsmän: Chen, Linlin, Xue, Feng, Xu, Jia, He, Jinwei, Fu, Wenzhen, Zhang, Zhenlin, Kang, Qinglin
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732320/
https://ncbi.nlm.nih.gov/pubmed/31347283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.904
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