Cyclic O(3) exposure synergizes with aging leading to memory impairment in male APOEε3, but not APOEε4, targeted replacement mice

The etiology of late-onset Alzheimer’s disease (LOAD) is unknown. Recent epidemiological studies suggest that exposure to high levels of ozone (O(3)) may be a risk factor for LOAD. Nonetheless, whether and how O(3) exposure contributes to AD development remains to be determined. In this study, we te...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Jiang, Chunsun, Stewart, Luke T., Kuo, Hui-Chien, McGilberry, William, Wall, Stephanie B., Liang, Bill, van Groen, Thomas, Bailey, Shannon M., Kim, Young-il, Tipple, Trent E., Jones, Dean P., McMahon, Lori L., Liu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732233/
https://ncbi.nlm.nih.gov/pubmed/31207469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.05.006
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