Cyclic O(3) exposure synergizes with aging leading to memory impairment in male APOEε3, but not APOEε4, targeted replacement mice

The etiology of late-onset Alzheimer’s disease (LOAD) is unknown. Recent epidemiological studies suggest that exposure to high levels of ozone (O(3)) may be a risk factor for LOAD. Nonetheless, whether and how O(3) exposure contributes to AD development remains to be determined. In this study, we te...

詳細記述

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書誌詳細
出版年:Neurobiol Aging
主要な著者: Jiang, Chunsun, Stewart, Luke T., Kuo, Hui-Chien, McGilberry, William, Wall, Stephanie B., Liang, Bill, van Groen, Thomas, Bailey, Shannon M., Kim, Young-il, Tipple, Trent E., Jones, Dean P., McMahon, Lori L., Liu, Rui-Ming
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732233/
https://ncbi.nlm.nih.gov/pubmed/31207469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.05.006
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