Microenvironment-sensing, nanocarrier-mediated delivery of combination chemotherapy for pancreatic cancer

Limited effectiveness of Raf and MEK inhibitors has impelled the interest to use the inhibitors of Extra-cellular Receptor Kinase (ERK) pathway in combination with Gemcitabine (GEM) in pancreatic cancer. However, off-target abundance of ERK receptors, challenging physico-chemical properties, and dos...

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Veröffentlicht in:J Cell Commun Signal
Hauptverfasser: Ray, Priyanka, Nair, Gauthami, Ghosh, Arnab, Banerjee, Snigdha, Golovko, Mikhail Y., Banerjee, Sushanta K., Reindl, Katie M., Mallik, Sanku, Quadir, Mohiuddin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732147/
https://ncbi.nlm.nih.gov/pubmed/30915617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-019-00514-w
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