Distinct Molecular Trajectories Converge to Induce Naive Pluripotency

Understanding how cell identity transitions occur and whether there are multiple paths between the same beginning and end states are questions of wide interest. Here we show that acquisition of naive pluripotency can follow transcriptionally and mechanistically distinct routes. Starting from post-im...

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Gepubliceerd in:Cell Stem Cell
Hoofdauteurs: Stuart, Hannah T., Stirparo, Giuliano G., Lohoff, Tim, Bates, Lawrence E., Kinoshita, Masaki, Lim, Chee Y., Sousa, Elsa J., Maskalenka, Katsiaryna, Radzisheuskaya, Aliaksandra, Malcolm, Andrew A., Alves, Mariana R.P., Lloyd, Rebecca L., Nestorowa, Sonia, Humphreys, Peter, Mansfield, William, Reik, Wolf, Bertone, Paul, Nichols, Jennifer, Göttgens, Berthold, Silva, José C.R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731995/
https://ncbi.nlm.nih.gov/pubmed/31422912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.07.009
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